GeoVax Announces License Agreement With NIH To Support COVID-19 Vaccine Development
a biotechnology company developing human immunotherapies and vaccines against infectious diseases and cancer, these days declared the
sign language of a Patentand Biological Materials License Agreement with the National Institute of allergic reaction and Infectious Diseases
(NIAID), a part of the National Institutes of Health (NIH), in support of GeoVax’s development of a immunogen against SARS-CoV-2, the
virus that causes COVID-19.The Patent License Agreement to GeoVax includes access to NIAID’s patent rights within the stabilised SPIKE
supermolecule, that is that the supermolecule that SARS-CoV-2 uses to realize entry into The License Agreement permits GeoVax to use
these materials and patent rights closely-held by agencies of the us Department of Health and Human Services (HHS) together with the
Company’s proprietarytechnology for the creation of a preventive changed Vaccinia national capital Virus-Virus Like Particle (MVA-VLP)
immunogen that primes and/or boosts the system against COVID-19. The agreement provides GeoVax with nonexclusive rights to develop,
manufacture and commercialize its COVID-19 immunogen. money terms of the License Agreement weren't disclosed. David Dodd, GeoVax
President and corporate executive, commented, “The sign language of this license agreement with NIAID is a very important event for our in
progress COVID-19 immunogen development program and is reflective of our optimism and commitment to speedily advancing the program.
This agreement includes the exploitation rights to the NIH MVA backbone for our SARS-CoV-2 immunogen, arising from the laboratory of Dr.
Claude Bernard nonvascular plant of the NIAID Laboratory of microorganism Diseases (LVD). GeoVax applauds the career and long-run
analysis contributions to antiviral immunogen backbones created by Dr. Claude Bernard nonvascular plant et al in his laboratory.” To date,
GeoVax has designed and made four COVID-19 immunogen candidates, with the goal that one can offer a single-dose, universal
immunogen effective against multiple coronavirus strains. presymptomatic tiny animal studies for the primary candidate area unit presently
being conducted together with researchers at the University of TX Medical Branch at Galveston (UTMB), and therefore the Company intends
to accelerate tiny animal testing with initial results expected before long. additionally, GeoVax continues active discussions and negotiations
associated with further funding support, likewise as securing the required producing resources to proceed into clinical development as
before long as potential.Mr. Dodd added, “We anticipate that multiple COVID-19 vaccines are necessary for the goal of broad public health
protection, particularly in addressing the preventive wants among populations with compromised immune systems, together with individuals
with co-morbidities and older adults.The GV-MVA-VLPTM platform, with the established and recognized history of the security of MVA and
different potential effectiveness, sturdiness and producing attributes, if with success developed, can become a essential immunogen to
handle COVID-19 and doubtless connected infectious threats.” Coronaviruses area unit common in several species of animals, together with
kookie and birds.These viruses will evolve to cross the animal species and infect humans and quickly unfold from person to person leading
to fatal however rare metastasis infections.Recent epidemics with severe acute respiratory syndrome and MERS coronaviruses resulted in
774 and 858 deaths, severally.Since 2015 there haven't been any cases of severe acute respiratory syndrome and MERS reported ,
however in January 2020, World Health Organization (WHO) known a completely unique coronavirus, recently named SARS-CoV-2, within
the town of urban center, China.On January thirty one, 2020 the UN agency declared the novel coronavirus to be a worldwide health
emergency, and on March eleven, 2020 the UN agency declared a worldwide pandemic. Worldwide, over forty one million individuals are
infected (over eight.3 million within the U.S.), with over one.1 million deaths (over two hundred,000 within the U.S). things is fluid, with the
infection and death statistics ever-changing considerably on an everyday basis.
may be a clinical-stage biotechnology company developing human immunogens against infectious diseases and cancer employing a novel
proprietary changed Vaccinia Ankara-Virus Like Particle (MVA-VLP) based mostly vaccine platform. On this platform, MVA, an oversized
microorganism vector capable of carrying many immunogen antigens, expresses proteins that assemble into VLP immunogens inside (in
vivo) the person receiving the immunogen.the assembly of VLPs within the person being immunized mimics virus production in a very
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| GeoVax Announces License Agreement With NIH To Support COVID-19 Vaccine Development |
natural infection, stimulating each the body substance and cellular arms of the system to The MVA-VLP derived vaccines will elicit sturdy
immune responses within the host kind of like a live-attenuated virus, whereas providing the security characteristics of a replication-
defective vector.GeoVax’s current development programs area unit targeted on preventive vaccines against COVID-19, HIV, Zika Virus,
viral infection viruses (Ebola, Sudan, Marburg, and Lassa), and protozoal infection, likewise as therapeutic vaccines the corporate has
designed a preventive HIV immunogen candidate to fight against the subtype of HIV current within the business markets of the Americas,
Western Europe, Japan, and Australia.Human clinical trials for our program are conducted and managed within the us by the HIV
immunogen Trials Network (HVTN) with the support of the National Institutes of Health (NIH). GeoVax’s HIV immunogen candidate is
additionally a part of 2 separate cooperative efforts to use its innovative factor medical aid approach toward a practical cure for HIV.
This unharness contains progressive statements concerning the recent license granted to GeoVax by the NIH and GeoVax’s merchandise
beneath development.The words “believe,” “may,” “estimate,” “continue,” “anticipate,” “intend,” “should,” “plan,” “could,” “target,” “potential,”
“is possible,” “will,” “expect” and similar expressions, as they relate to USA, area unit meant to we've based mostly these progressive
statements for the most part supported our plans concerning merchandise beneath development, our condition, results of operations, business strategy and money wants.
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| GeoVax Announces License Agreement With NIH To Support COVID-19 Vaccine Development |
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